Nicotine Replacement Guide



Nicotine Patches
Nicotine Gum
Rx Nicotine Inhaler Rx Nicotine Spray Rx Bupropion HCI SR Tablet
Brand Name Nicotrol® Nicoderm® CQ Nicorette® Nicotrol® Inhaler Nicotrol® NS Zyban™
Product Strengths 15 mg 21 mg, 14 mg, 7mg 2 mg, 4 mg 10 mg/cartridge 10 mg/ml 150 mg
Initial Dosing 1 patch/16 hours 1 patch/24 or 16 hrs. 1 piece every 1 to 2 hrs. 6-16 cartridges/day 1-2 doses/hr.

(1 dose=2 sprays or 1 per nostril)
150 mg/day
(days 1-3)

300 mg/day
(after day 3)
MAX Dosing Same as above Same as above 24 pieces per day 16 cartridges/day 5 doses/hr or 40 doses/day 300 mg/day
Time to Peak Plasma Level 5-10 hours 5-10 hours 20-30 minutes 15 mins. 5-7 mins. 3 hrs.
Mfr's Recommended Tx Duration 6 weeks 10 weeks 12 weeks 12 weeks 12 weeks 7-12 weeks
Adverse Reactions 50% experience mild skin reactions (rotate and use steroid cream); vivid dreams, sleep disturbances while on the patch for 24 hours (remove at bed time) Mouth soreness, hiccups, dyspepsia, jaw ache (usually mild & transient; correct technique) 40% experience mouth & throat irritation (resolved through regular use); dyspepsia Local transient irritation in the nose & throat, watery eyes, sneezing & cough Dry mouth; insomnia (avoid bedtime dose); shakiness & skin rash
Unique Product Contraindications Severe eczema or other skin diseases which may be exacerbated by the patch; allergy to adhesive tape  Severe TMJ disease or other jaw problems; presence of dentures or other dental appliances Allergy to menthol Asthma, rhinitis, nasal polyps, or sinusitis Seizure disorder; current use of Wellbutrin or bupropion; current or prior dx of bulimia, or anorexia nervosa; concurrent or recent use of MAO inhibitors; bupropion allergy
Consumer Information (800)


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